Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Ambry Genetics | RCV002870500 | SCV003643884 | uncertain significance | Inborn genetic diseases | 2022-08-30 | criteria provided, single submitter | clinical testing | The c.2494C>G (p.P832A) alteration is located in exon 16 (coding exon 16) of the TUBGCP6 gene. This alteration results from a C to G substitution at nucleotide position 2494, causing the proline (P) at amino acid position 832 to be replaced by an alanine (A). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |