ClinVar Miner

Submissions for variant NM_021738.3(SVIL):c.3776T>C (p.Met1259Thr)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Genetic Services Laboratory, University of Chicago RCV003151666 SCV003840097 benign not specified 2022-06-27 no assertion criteria provided clinical testing
PreventionGenetics, part of Exact Sciences RCV003984353 SCV004796367 likely benign SVIL-related disorder 2021-11-24 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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