ClinVar Miner

Submissions for variant NM_021913.5(AXL):c.1021A>T (p.Ser341Cys)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV005296799 SCV005961426 uncertain significance not specified 2025-01-08 criteria provided, single submitter clinical testing The c.1021A>T (p.S341C) alteration is located in exon 8 (coding exon 8) of the AXL gene. This alteration results from a A to T substitution at nucleotide position 1021, causing the serine (S) at amino acid position 341 to be replaced by a cysteine (C). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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