ClinVar Miner

Submissions for variant NM_022095.4(ZNF335):c.3639C>T (p.Thr1213=)

gnomAD frequency: 0.00016  dbSNP: rs191074858
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 3
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Genetic Services Laboratory, University of Chicago RCV000192624 SCV000249505 uncertain significance not specified 2015-05-11 criteria provided, single submitter clinical testing
Invitae RCV000958466 SCV001105313 likely benign not provided 2023-05-05 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003927813 SCV004738421 likely benign ZNF335-related condition 2019-05-07 criteria provided, single submitter clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.