Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Ambry Genetics | RCV004981322 | SCV005557980 | uncertain significance | Inborn genetic diseases | 2024-09-08 | criteria provided, single submitter | clinical testing | The c.9311G>C (p.G3104A) alteration is located in exon 65 (coding exon 64) of the CDH23 gene. This alteration results from a G to C substitution at nucleotide position 9311, causing the glycine (G) at amino acid position 3104 to be replaced by an alanine (A). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |