ClinVar Miner

Submissions for variant NM_022158.4(FN3K):c.826C>G (p.Arg276Gly)

gnomAD frequency: 0.00001  dbSNP: rs117622449
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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004242648 SCV003760744 uncertain significance not specified 2022-06-17 criteria provided, single submitter clinical testing The c.826C>G (p.R276G) alteration is located in exon 6 (coding exon 6) of the FN3K gene. This alteration results from a C to G substitution at nucleotide position 826, causing the arginine (R) at amino acid position 276 to be replaced by a glycine (G). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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