ClinVar Miner

Submissions for variant NM_022552.5(DNMT3A):c.2710C>T (p.Pro904Ser) (rs1558650888)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Murat Gunel Laboratory,Yale University RCV000785978 SCV000924296 likely pathogenic Glioblastoma 2019-06-11 no assertion criteria provided clinical testing Somatic mutation DNMT3A p.P904S is found in a patient with recurrent GBM, localizing to the highly conserved catalytic domain.

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