ClinVar Miner

Submissions for variant NM_024006.4(VKORC1):c.-1639G>A (rs9923231)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000377657 SCV000331715 other not provided 2018-08-08 criteria provided, single submitter clinical testing
GeneDx RCV000603173 SCV000724152 likely benign not specified 2018-03-09 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine RCV000002295 SCV000202013 drug response Warfarin response 2006-12-16 no assertion criteria provided clinical testing
OMIM RCV000002295 SCV000022453 drug response Warfarin response 2012-11-03 no assertion criteria provided literature only

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