Submissions for variant NM_024022.2(TMPRSS3):c.617-3_617-2dup

dbSNP: rs34966432

Total submissions: 7

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	RCV000039363	SCV000063047	benign	not specified	2007-02-16	criteria provided, single submitter	clinical testing
PreventionGenetics, part of Exact Sciences	RCV000039363	SCV000314238	benign	not specified		criteria provided, single submitter	clinical testing
Eurofins Ntd Llc (ga)	RCV000039363	SCV000345447	benign	not specified	2016-08-26	criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000310575	SCV000436168	likely benign	Nonsyndromic Hearing Loss, Recessive	2016-06-14	criteria provided, single submitter	clinical testing
GeneDx	RCV000039363	SCV000730616	benign	not specified	2017-09-15	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV001807765	SCV002058046	benign	Autosomal recessive nonsyndromic hearing loss 8	2023-11-29	criteria provided, single submitter	clinical testing
Invitae	RCV002054756	SCV002410667	benign	not provided	2024-02-01	criteria provided, single submitter	clinical testing