Submissions for variant NM_024426.6(WT1):c.1265-32C>A

gnomAD frequency: 0.12726  dbSNP: rs2234593

Total submissions: 10

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
PreventionGenetics, part of Exact Sciences	RCV000253201	SCV000314309	benign	not specified		criteria provided, single submitter	clinical testing
GeneDx	RCV000837113	SCV000978963	benign	not provided	2018-06-16	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genome-Nilou Lab	RCV000210050	SCV002515029	benign	Drash syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002243891	SCV002515031	benign	Frasier syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002243892	SCV002515032	benign	Meacham syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002243893	SCV002515033	benign	Nephrotic syndrome, type 4	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002243890	SCV002515034	benign	Wilms tumor 1	2021-12-05	criteria provided, single submitter	clinical testing
KCCC/NGS Laboratory, Kuwait Cancer Control Center	RCV002243890	SCV004016259	benign	Wilms tumor 1	2023-07-07	criteria provided, single submitter	clinical testing
Breakthrough Genomics, Breakthrough Genomics	RCV000837113	SCV005323080	benign	not provided		criteria provided, single submitter	not provided
Human Genetics Disease in Children – Taif University, Taif University	RCV000210050	SCV000265970	benign	Drash syndrome	2016-01-01	no assertion criteria provided	clinical testing