Submissions for variant NM_024426.6(WT1):c.785-20G>T

gnomAD frequency: 0.00663  dbSNP: rs5030168

Total submissions: 10

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
PreventionGenetics, part of Exact Sciences	RCV000242096	SCV000314318	benign	not specified		criteria provided, single submitter	clinical testing
GeneDx	RCV000242096	SCV000730735	likely benign	not specified	2017-05-17	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae	RCV002058330	SCV002436612	benign	Drash syndrome; Frasier syndrome; Wilms tumor 1; 11p partial monosomy syndrome	2024-01-31	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002244671	SCV002515058	benign	Drash syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002244670	SCV002515059	benign	Frasier syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002244672	SCV002515060	benign	Meacham syndrome	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002244673	SCV002515061	benign	Nephrotic syndrome, type 4	2021-12-05	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV002244669	SCV002515062	benign	Wilms tumor 1	2021-12-05	criteria provided, single submitter	clinical testing
Genome Diagnostics Laboratory, Amsterdam University Medical Center	RCV000242096	SCV001807173	benign	not specified		no assertion criteria provided	clinical testing
Genome Diagnostics Laboratory, University Medical Center Utrecht	RCV000242096	SCV001932739	benign	not specified		no assertion criteria provided	clinical testing