ClinVar Miner

Submissions for variant NM_024675.4(PALB2):c.3467_3468del (p.Asp1156fs)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV004589343 SCV005083650 likely pathogenic Familial cancer of breast 2024-05-15 criteria provided, single submitter clinical testing This variant is considered likely pathogenic. This variant creates a frameshift predicted to result in the incorporation of abnormal amino acid sequence into the protein product and abnormal protein elongation.

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