ClinVar Miner

Submissions for variant NM_025077.4(TOE1):c.-20G>A (rs753502884)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000476955 SCV000557581 likely benign MYH-associated polyposis 2020-08-31 criteria provided, single submitter clinical testing
Ambry Genetics RCV000573715 SCV000666465 likely benign Hereditary cancer-predisposing syndrome 2016-01-19 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign
Color Health, Inc RCV000573715 SCV000690545 likely benign Hereditary cancer-predisposing syndrome 2016-05-03 criteria provided, single submitter clinical testing
GeneDx RCV000610552 SCV000717541 likely benign not specified 2017-03-29 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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