ClinVar Miner

Submissions for variant NM_025216.3(WNT10A):c.512G>A (p.Arg171His)

gnomAD frequency: 0.00006  dbSNP: rs199737793
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 3
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV000878034 SCV001020874 likely benign Odonto-onycho-dermal dysplasia; Tooth agenesis, selective, 4 2024-12-09 criteria provided, single submitter clinical testing
Natera, Inc. RCV001825777 SCV002078825 likely benign SchC6pf-Schulz-Passarge syndrome 2020-01-27 no assertion criteria provided clinical testing
PreventionGenetics, part of Exact Sciences RCV004530879 SCV004722828 likely benign WNT10A-related disorder 2022-05-09 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.