Submissions for variant NM_030667.3(PTPRO):c.1106-10T>A

gnomAD frequency: 0.84939  dbSNP: rs4764199

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV001683757	SCV001901475	benign	not provided	2018-11-12	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV001683757	SCV002373327	benign	not provided	2025-02-03	criteria provided, single submitter	clinical testing
Breakthrough Genomics, Breakthrough Genomics	RCV001683757	SCV005235653	benign	not provided		criteria provided, single submitter	not provided
Genetic Testing Lab, Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences	RCV001261437	SCV001438727	drug response	Corticosteroids response	2020-01-12	no assertion criteria provided	research	Depending upon response to standard corticosteroid therapy, patients were classified to be either Steroid resistant (SRNS) or steroid sensitive (SSNS). Patients in remission within 4 weeks of corticosteroid therapy were classified as steroid sensitive nephrotic syndrome (SSNS). Patients not in remission within 4 weeks of corticosteroid therapy were classified as Steroid resistant nephrotic syndrome (SRNS).
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen	RCV001528296	SCV001739811	benign	not specified		no assertion criteria provided	clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+	RCV001528296	SCV001953443	benign	not specified		no assertion criteria provided	clinical testing