Submissions for variant NM_032043.2(BRIP1):c.195A>G (p.Gln65=) (rs141436143)

Total submissions: 9

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV000212297	SCV000210854	benign	not specified	2014-09-09	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics	RCV000160348	SCV000213547	likely benign	Hereditary cancer-predisposing syndrome	2014-08-13	criteria provided, single submitter	clinical testing
Invitae	RCV001081274	SCV000252874	benign	Familial cancer of breast; Fanconi anemia, complementation group J	2019-12-31	criteria provided, single submitter	clinical testing
Counsyl	RCV000409428	SCV000490013	likely benign	Fanconi anemia, complementation group J	2016-09-26	criteria provided, single submitter	clinical testing
Counsyl	RCV000410958	SCV000490014	likely benign	Neoplasm of ovary	2016-09-26	criteria provided, single submitter	clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV000212297	SCV000600896	likely benign	not specified	2017-04-20	criteria provided, single submitter	clinical testing
Color	RCV000160348	SCV000684173	benign	Hereditary cancer-predisposing syndrome	2016-10-03	criteria provided, single submitter	clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV000759702	SCV000889202	likely benign	not provided	2017-04-20	criteria provided, single submitter	clinical testing
Mendelics	RCV000990043	SCV001140807	likely benign	Familial cancer of breast	2019-05-28	criteria provided, single submitter	clinical testing