ClinVar Miner

Submissions for variant NM_032043.2(BRIP1):c.2811T>C (p.Asp937=) (rs374335608)

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Total submissions: 7
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163081 SCV000213583 likely benign Hereditary cancer-predisposing syndrome 2014-10-14 criteria provided, single submitter clinical testing
Invitae RCV000233012 SCV000291025 likely benign not provided 2019-02-20 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000317394 SCV000404584 uncertain significance Neoplasm of the breast 2016-06-14 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000374312 SCV000404585 uncertain significance Fanconi anemia 2016-06-14 criteria provided, single submitter clinical testing
GeneDx RCV000440198 SCV000517424 likely benign not specified 2016-03-14 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Integrated Genetics/Laboratory Corporation of America RCV000440198 SCV000699704 likely benign not specified 2019-07-18 criteria provided, single submitter clinical testing
Color RCV000163081 SCV000912103 likely benign Hereditary cancer-predisposing syndrome 2017-11-16 criteria provided, single submitter clinical testing

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