Submissions for variant NM_032043.2(BRIP1):c.595C>T (p.Leu199=) (rs144969738)

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Ambry Genetics	RCV000215945	SCV000274260	likely benign	Hereditary cancer-predisposing syndrome	2015-03-06	criteria provided, single submitter	clinical testing
Counsyl	RCV000409950	SCV000490079	likely benign	Fanconi anemia, complementation group J	2016-10-31	criteria provided, single submitter	clinical testing
Counsyl	RCV000411438	SCV000490080	likely benign	Neoplasm of ovary	2016-10-31	criteria provided, single submitter	clinical testing
GeneDx	RCV000601018	SCV000726980	likely benign	not specified	2018-01-19	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Institute for Biomarker Research,Medical Diagnostic Laboratories, L.L.C.	RCV000215945	SCV000747817	likely benign	Hereditary cancer-predisposing syndrome	2018-01-16	criteria provided, single submitter	clinical testing
Invitae	RCV000230450	SCV000291053	likely benign	Familial cancer of breast; Fanconi anemia, complementation group J	2017-12-07	criteria provided, single submitter	clinical testing