Submissions for variant NM_032043.3(BRIP1):c.380-17dup

dbSNP: rs545021924

Total submissions: 9

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV000160345	SCV000210851	benign	Hereditary cancer-predisposing syndrome	2014-01-21	criteria provided, single submitter	clinical testing	The variant is found in BR-OV-HEREDIC,HEREDICANCER panel(s).
Counsyl	RCV000411395	SCV000489877	likely benign	Fanconi anemia complementation group J	2016-06-27	criteria provided, single submitter	clinical testing
Counsyl	RCV000408968	SCV000489878	likely benign	Ovarian neoplasm	2016-06-27	criteria provided, single submitter	clinical testing
Color Diagnostics, LLC DBA Color Health	RCV000160345	SCV000684274	likely benign	Hereditary cancer-predisposing syndrome	2015-04-07	criteria provided, single submitter	clinical testing
PreventionGenetics, part of Exact Sciences	RCV000679788	SCV000807149	benign	not specified	2017-02-17	criteria provided, single submitter	clinical testing
Invitae	RCV002053920	SCV002410188	benign	Familial cancer of breast; Fanconi anemia complementation group J	2024-01-31	criteria provided, single submitter	clinical testing
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV000679788	SCV002551215	likely benign	not specified	2023-08-15	criteria provided, single submitter	clinical testing
CHEO Genetics Diagnostic Laboratory, Children's Hospital of Eastern Ontario	RCV003149973	SCV003837720	likely benign	Breast and/or ovarian cancer	2023-01-06	criteria provided, single submitter	clinical testing
Myriad Genetics, Inc.	RCV003315955	SCV004019346	benign	Familial cancer of breast	2023-02-28	criteria provided, single submitter	clinical testing	This variant is considered benign. This variant is intronic and is not expected to impact mRNA splicing.