Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Ambry Genetics | RCV004930791 | SCV005590046 | uncertain significance | not specified | 2024-10-20 | criteria provided, single submitter | clinical testing | The c.325G>C (p.G109R) alteration is located in exon 4 (coding exon 4) of the HAGHL gene. This alteration results from a G to C substitution at nucleotide position 325, causing the glycine (G) at amino acid position 109 to be replaced by an arginine (R). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |