ClinVar Miner

Submissions for variant NM_033360.4(KRAS):c.*298T>G

gnomAD frequency: 0.45514  dbSNP: rs712
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Illumina Laboratory Services, Illumina RCV000382642 SCV000377737 likely benign Noonan syndrome 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV001520594 SCV001729727 benign RASopathy 2020-12-04 criteria provided, single submitter clinical testing
GeneDx RCV000860174 SCV001935175 benign not provided 2015-03-03 criteria provided, single submitter clinical testing This variant is associated with the following publications: (PMID: 24552817, 25961464, 26535719)
Genome Diagnostics Laboratory, The Hospital for Sick Children RCV001813239 SCV002060520 benign Noonan syndrome and Noonan-related syndrome 2021-07-13 criteria provided, single submitter clinical testing

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