ClinVar Miner

Submissions for variant NM_033360.4(KRAS):c.112-10C>T

gnomAD frequency: 0.00004  dbSNP: rs760989619
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV000559208 SCV000659083 likely benign RASopathy 2023-12-21 criteria provided, single submitter clinical testing
GeneDx RCV000681291 SCV000808753 likely benign not provided 2018-05-21 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV000681291 SCV002050194 likely benign not provided 2021-11-24 criteria provided, single submitter clinical testing

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