ClinVar Miner

Submissions for variant NM_054021.2(GPR101):c.1102G>A (p.Glu368Lys)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV002624055 SCV003513550 benign not provided 2022-10-26 criteria provided, single submitter clinical testing
Ambry Genetics RCV004070675 SCV004067975 uncertain significance not specified 2023-06-30 criteria provided, single submitter clinical testing The c.1102G>A (p.E368K) alteration is located in exon 1 (coding exon 1) of the GPR101 gene. This alteration results from a G to A substitution at nucleotide position 1102, causing the glutamic acid (E) at amino acid position 368 to be replaced by a lysine (K). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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