ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.12G>A (p.Lys4=) (rs781166242)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000582002 SCV000691220 likely benign Hereditary cancer-predisposing syndrome 2016-05-02 criteria provided, single submitter clinical testing
MVZ Praenatalmedizin und Genetik Nuernberg RCV000477694 SCV000494624 likely benign Familial cancer of breast 2017-02-01 no assertion criteria provided clinical testing This variant is predicted to be a silent mutation by multiple in silico analyses including in silico splicing predictions. Our patient harbors a BRCA2-pathogenic variant in parallel [BRCA2 c.1813dupA (het)].

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