ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.141C>T (p.Ser47=) (rs568912602)

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Total submissions: 8
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000164506 SCV000215157 likely benign Hereditary cancer-predisposing syndrome 2014-06-17 criteria provided, single submitter clinical testing
Color RCV000164506 SCV000686325 likely benign Hereditary cancer-predisposing syndrome 2015-08-11 criteria provided, single submitter clinical testing
Counsyl RCV000198476 SCV000490087 likely benign Fanconi anemia, complementation group O 2016-11-02 criteria provided, single submitter clinical testing
Counsyl RCV000410680 SCV000490088 likely benign Breast-ovarian cancer, familial 3 2016-11-02 criteria provided, single submitter clinical testing
GeneDx RCV000445007 SCV000521532 likely benign not specified 2017-07-27 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000198476 SCV000253637 likely benign Fanconi anemia, complementation group O 2017-10-26 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000445007 SCV000602134 likely benign not specified 2017-03-02 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000760057 SCV000889816 likely benign not provided 2018-03-07 criteria provided, single submitter clinical testing

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