Submissions for variant NM_058216.3(RAD51C):c.141C>T (p.Ser47=) (rs568912602)

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Total submissions: 10

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Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Ambry Genetics	RCV000164506	SCV000215157	likely benign	Hereditary cancer-predisposing syndrome	2019-09-11	criteria provided, single submitter	clinical testing	Synonymous alterations with insufficient evidence to classify as benign
Invitae	RCV000198476	SCV000253637	likely benign	Fanconi anemia, complementation group O	2019-12-31	criteria provided, single submitter	clinical testing
Counsyl	RCV000198476	SCV000490087	likely benign	Fanconi anemia, complementation group O	2016-11-02	criteria provided, single submitter	clinical testing
Counsyl	RCV000410680	SCV000490088	likely benign	Breast-ovarian cancer, familial 3	2016-11-02	criteria provided, single submitter	clinical testing
GeneDx	RCV000445007	SCV000521532	likely benign	not specified	2017-07-27	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV000445007	SCV000602134	likely benign	not specified	2017-03-02	criteria provided, single submitter	clinical testing
Color	RCV000164506	SCV000686325	likely benign	Hereditary cancer-predisposing syndrome	2015-08-11	criteria provided, single submitter	clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV000760057	SCV000889816	likely benign	not provided	2018-03-07	criteria provided, single submitter	clinical testing
Mendelics	RCV000198476	SCV001140707	likely benign	Fanconi anemia, complementation group O	2019-05-28	criteria provided, single submitter	clinical testing
Integrated Genetics/Laboratory Corporation of America	RCV000445007	SCV001362535	likely benign	not specified	2019-08-27	criteria provided, single submitter	clinical testing

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