ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.435A>G (p.Pro145=) (rs555235745)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000581354 SCV000691237 likely benign Hereditary cancer-predisposing syndrome 2017-01-19 criteria provided, single submitter clinical testing
GeneDx RCV000599947 SCV000716403 likely benign not specified 2017-02-26 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000648279 SCV000770093 likely benign not provided 2018-08-28 criteria provided, single submitter clinical testing

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