ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.449G>T (p.Gly150Val)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV005249925 SCV005897471 likely pathogenic Breast-ovarian cancer, familial, susceptibility to, 3 2024-11-25 criteria provided, single submitter clinical testing This variant is considered likely pathogenic. Functional studies indicate this variant impacts protein function [PMID: 39299233]. This variant is expected to disrupt protein structure [Myriad internal data].

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