ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.513C>T (p.Asp171=) (rs140279158)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163474 SCV000214029 likely benign Hereditary cancer-predisposing syndrome 2015-04-23 criteria provided, single submitter clinical testing
Color RCV000163474 SCV000686359 likely benign Hereditary cancer-predisposing syndrome 2016-01-05 criteria provided, single submitter clinical testing
GeneDx RCV000507662 SCV000729699 likely benign not specified 2017-10-23 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000205647 SCV000262131 likely benign Fanconi anemia, complementation group O 2017-11-08 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000507662 SCV000602141 likely benign not specified 2017-05-18 criteria provided, single submitter clinical testing

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