ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.783A>G (p.Leu261=) (rs138643096)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000163867 SCV000214454 likely benign Hereditary cancer-predisposing syndrome 2015-01-05 criteria provided, single submitter clinical testing
Invitae RCV000759336 SCV000253645 likely benign not provided 2019-01-30 criteria provided, single submitter clinical testing
GeneDx RCV000426427 SCV000515582 likely benign not specified 2017-11-01 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000426427 SCV000602147 likely benign not specified 2017-06-23 criteria provided, single submitter clinical testing
Color RCV000163867 SCV000686390 likely benign Hereditary cancer-predisposing syndrome 2015-12-28 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759336 SCV000888604 likely benign not provided 2017-06-23 criteria provided, single submitter clinical testing

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