ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.837+14A>G

gnomAD frequency: 0.00002  dbSNP: rs1057517644
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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Counsyl RCV000409894 SCV000490019 likely benign Fanconi anemia complementation group O 2016-09-28 criteria provided, single submitter clinical testing
Counsyl RCV000411529 SCV000490020 likely benign Breast-ovarian cancer, familial, susceptibility to, 3 2016-09-28 criteria provided, single submitter clinical testing
GeneDx RCV000441287 SCV000531722 likely benign not specified 2017-03-23 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health RCV000580220 SCV000686396 likely benign Hereditary cancer-predisposing syndrome 2017-04-13 criteria provided, single submitter clinical testing
Invitae RCV000409894 SCV002461225 likely benign Fanconi anemia complementation group O 2023-11-06 criteria provided, single submitter clinical testing

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