ClinVar Miner

Submissions for variant NM_058216.3(RAD51C):c.87T>C (p.Ser29=) (rs786203249)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000166476 SCV000217274 likely benign Hereditary cancer-predisposing syndrome 2014-10-29 criteria provided, single submitter clinical testing
Color RCV000166476 SCV000691278 likely benign Hereditary cancer-predisposing syndrome 2017-07-21 criteria provided, single submitter clinical testing
GeneDx RCV000431471 SCV000518245 likely benign not specified 2016-10-10 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Illumina Clinical Services Laboratory,Illumina RCV000333563 SCV000404315 uncertain significance Breast and Ovarian Cancer Susceptibility 2016-06-14 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000388046 SCV000404316 uncertain significance Fanconi anemia 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV000199492 SCV000253646 likely benign Fanconi anemia, complementation group O 2017-11-08 criteria provided, single submitter clinical testing

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