Total submissions: 6
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Eurofins Ntd Llc |
RCV000343380 | SCV000336516 | uncertain significance | not provided | 2015-10-23 | criteria provided, single submitter | clinical testing | |
Invitae | RCV001083769 | SCV001009072 | likely benign | Autosomal recessive polycystic kidney disease | 2024-01-25 | criteria provided, single submitter | clinical testing | |
Illumina Laboratory Services, |
RCV001083769 | SCV001321870 | uncertain significance | Autosomal recessive polycystic kidney disease | 2017-04-27 | criteria provided, single submitter | clinical testing | This variant was observed as part of a predisposition screen in an ostensibly healthy population. A literature search was performed for the gene, cDNA change, and amino acid change (where applicable). No publications were found based on this search. Allele frequency data from public databases did not allow this variant to be ruled in or out of causing disease. Therefore, this variant is classified as a variant of unknown significance. |
Genome- |
RCV001449587 | SCV001652738 | likely benign | Polycystic kidney disease 4 | 2021-05-18 | criteria provided, single submitter | clinical testing | |
Prevention |
RCV003977763 | SCV004792147 | likely benign | PKHD1-related disorder | 2019-03-25 | criteria provided, single submitter | clinical testing | This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications). |
Natera, |
RCV001083769 | SCV001463502 | uncertain significance | Autosomal recessive polycystic kidney disease | 2018-08-15 | no assertion criteria provided | clinical testing |