ClinVar Miner

Submissions for variant NM_177438.2(DICER1):c.2557A>G (p.Ile853Val) (rs61729795)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 3
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000563365 SCV000661801 likely benign Hereditary cancer-predisposing syndrome 2018-02-16 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: In silico models in agreement (benign),Subpopulation frequency in support of benign classification
ITMI RCV000120635 SCV000084796 not provided not specified 2013-09-19 no assertion provided reference population
Invitae RCV000203701 SCV000261767 benign DICER1-related pleuropulmonary blastoma cancer predisposition syndrome 2018-01-12 criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.