ClinVar Miner

Submissions for variant NM_177438.2(DICER1):c.3553G>A (p.Ala1185Thr) (rs150514959)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000231625 SCV000291663 likely benign not provided 2019-02-01 criteria provided, single submitter clinical testing
Ambry Genetics RCV000573896 SCV000661803 uncertain significance Hereditary cancer-predisposing syndrome 2017-04-06 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient evidence
Mendelics RCV000989255 SCV001139510 uncertain significance DICER1-related pleuropulmonary blastoma cancer predisposition syndrome 2019-05-28 criteria provided, single submitter clinical testing
ITMI RCV000120639 SCV000084800 not provided not specified 2013-09-19 no assertion provided reference population
Clinical Genomics Lab,St. Jude Children's Research Hospital RCV000761100 SCV000891015 uncertain significance Acute myeloid leukemia 2016-11-07 no assertion criteria provided clinical testing

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