ClinVar Miner

Submissions for variant NM_177438.2(DICER1):c.5337G>A (p.Lys1779=) (rs111630745)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000575036 SCV000661812 likely benign Hereditary cancer-predisposing syndrome 2017-04-01 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Synonymous alterations with insufficient evidence to classify as benign
Invitae RCV000231262 SCV000291714 benign DICER1-related pleuropulmonary blastoma cancer predisposition syndrome 2017-12-11 criteria provided, single submitter clinical testing
PreventionGenetics RCV000851478 SCV000993766 likely benign not provided 2017-10-13 criteria provided, single submitter clinical testing

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