Submissions for variant NM_177438.3(DICER1):c.4206+9_4206+17del

gnomAD frequency: 0.01738  dbSNP: rs772457274

Total submissions: 8

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Labcorp Genetics (formerly Invitae), Labcorp	RCV000557083	SCV000658273	benign	DICER1-related tumor predisposition	2025-01-23	criteria provided, single submitter	clinical testing
GeneDx	RCV002225662	SCV002504346	likely benign	not provided	2019-08-07	criteria provided, single submitter	clinical testing	See Variant Classification Assertion Criteria.
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV001529522	SCV002551510	benign	not specified	2025-03-04	criteria provided, single submitter	clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano	RCV001529522	SCV002774290	benign	not specified	2021-08-03	criteria provided, single submitter	clinical testing
Department of Pathology and Laboratory Medicine, Sinai Health System	RCV000557083	SCV005912947	benign	DICER1-related tumor predisposition	2023-01-19	criteria provided, single submitter	clinical testing
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen	RCV001529522	SCV001743111	benign	not specified		no assertion criteria provided	clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	RCV001529522	SCV001972026	benign	not specified		no assertion criteria provided	clinical testing
Laboratory of Diagnostic Genome Analysis, Leiden University Medical Center (LUMC)	RCV001529522	SCV002036694	benign	not specified		no assertion criteria provided	clinical testing