ClinVar Miner

Submissions for variant NM_182643.3(DLC1):c.2665T>C (p.Ser889Pro)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004292098 SCV003954959 uncertain significance not specified 2023-05-03 criteria provided, single submitter clinical testing The c.2665T>C (p.S889P) alteration is located in exon 9 (coding exon 8) of the DLC1 gene. This alteration results from a T to C substitution at nucleotide position 2665, causing the serine (S) at amino acid position 889 to be replaced by a proline (P). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.
Fulgent Genetics, Fulgent Genetics RCV005047496 SCV005677836 uncertain significance Colorectal cancer 2024-03-21 criteria provided, single submitter clinical testing

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