ClinVar Miner

Submissions for variant NM_198578.3(LRRK2):c.149A>G (p.His50Arg)

gnomAD frequency: 0.03048  dbSNP: rs2256408
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Athena Diagnostics RCV000518786 SCV000614033 benign not specified 2017-01-30 criteria provided, single submitter clinical testing
Labcorp Genetics (formerly Invitae), Labcorp RCV000032408 SCV000640124 benign Autosomal dominant Parkinson disease 8 2025-01-27 criteria provided, single submitter clinical testing
GeneReviews RCV000032408 SCV000056064 unknown Autosomal dominant Parkinson disease 8 2012-09-13 no assertion criteria provided curation Converted during submission to Uncertain significance.

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