ClinVar Miner

List of variants in gene LRRK2 reported as benign for Autosomal dominant Parkinson disease 8

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Gene type:
ClinVar version:
Total variants: 102
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HGVS dbSNP gnomAD frequency
NM_198578.4(LRRK2):c.149G>A (p.Arg50His) rs2256408 0.96952
NM_198578.4(LRRK2):c.4872C>A (p.Gly1624=) rs1427263 0.70218
NM_198578.4(LRRK2):c.*979T>C rs10784548 0.61859
NM_198578.4(LRRK2):c.*736G>C rs1365770 0.61834
NM_198578.4(LRRK2):c.7190T>C (p.Met2397Thr) rs3761863 0.61824
NM_198578.4(LRRK2):c.*384C>T rs3886747 0.61718
NM_198578.4(LRRK2):c.*364A>C rs10878441 0.61691
NM_198578.4(LRRK2):c.4911A>G (p.Lys1637=) rs11176013 0.56443
NM_198578.4(LRRK2):c.5457T>C (p.Gly1819=) rs10878371 0.56374
NM_198578.4(LRRK2):c.5949-2490G>A rs6581668 0.50703
NM_198578.4(LRRK2):c.457T>C (p.Leu153=) rs10878245 0.50692
NM_198578.4(LRRK2):c.1102-10C>A rs7955902 0.31995
NM_198578.4(LRRK2):c.4939T>A (p.Ser1647Thr) rs11564148 0.26687
NM_198578.4(LRRK2):c.6324G>A (p.Glu2108=) rs10878405 0.26650
NM_198578.4(LRRK2):c.*96T>C rs66737902 0.13862
NM_198578.4(LRRK2):c.7155A>G (p.Gly2385=) rs33962975 0.11278
NM_198578.4(LRRK2):c.1653C>G (p.Asn551Lys) rs7308720 0.10004
NM_198578.4(LRRK2):c.2857T>C (p.Leu953=) rs7966550 0.08994
NM_198578.4(LRRK2):c.4269G>A (p.Lys1423=) rs11175964 0.05959
NM_198578.4(LRRK2):c.2167A>G (p.Ile723Val) rs10878307 0.04677
NM_198578.4(LRRK2):c.4624C>T (p.Pro1542Ser) rs33958906 0.03091
NM_198578.3(LRRK2):c.149A>G (p.His50Arg) rs2256408 0.03048
NM_198578.4(LRRK2):c.*1446T>A rs12422278 0.02939
NM_198578.4(LRRK2):c.6844-14_6844-13insA rs150964683 0.01681
NM_198578.4(LRRK2):c.1182-4A>G rs7135747 0.01555
NM_198578.4(LRRK2):c.4317+12del rs200829235 0.01470
NM_198578.4(LRRK2):c.3778-9C>T rs114948984 0.01375
NM_198578.4(LRRK2):c.5509+20A>C rs11564134 0.01309
NM_198578.4(LRRK2):c.6241A>G (p.Asn2081Asp) rs33995883 0.01276
NM_198578.4(LRRK2):c.867C>T (p.Asn289=) rs17490713 0.01182
NM_198578.4(LRRK2):c.4937T>C (p.Met1646Thr) rs35303786 0.01047
NM_198578.4(LRRK2):c.*1464T>G rs17491828 0.01033
NM_198578.4(LRRK2):c.*1482A>G rs17491835 0.01032
NM_198578.4(LRRK2):c.3784C>G (p.Pro1262Ala) rs4640000 0.00717
NM_198578.4(LRRK2):c.4229C>T (p.Thr1410Met) rs72546327 0.00621
NM_198578.4(LRRK2):c.*346A>G rs17520676 0.00565
NM_198578.4(LRRK2):c.4541G>A (p.Arg1514Gln) rs35507033 0.00526
NM_198578.4(LRRK2):c.4318-6C>T rs56082834 0.00339
NM_198578.4(LRRK2):c.*1181C>T rs147956597 0.00296
NM_198578.4(LRRK2):c.5163A>G (p.Ser1721=) rs79909111 0.00293
NM_198578.4(LRRK2):c.1000G>A (p.Glu334Lys) rs78501232 0.00266
NM_198578.4(LRRK2):c.5510-9A>G rs41286460 0.00252
NM_198578.4(LRRK2):c.*123A>C rs73277568 0.00159
NM_198578.4(LRRK2):c.225G>A (p.Ala75=) rs75054132 0.00146
NM_198578.4(LRRK2):c.736A>C (p.Asn246His) rs150050676 0.00141
NM_198578.4(LRRK2):c.1740A>T (p.Leu580Phe) rs145906734 0.00132
NM_198578.4(LRRK2):c.5015+13T>A rs142483656 0.00124
NM_198578.4(LRRK2):c.3333G>T (p.Gln1111His) rs78365431 0.00121
NM_198578.4(LRRK2):c.2022A>C (p.Val674=) rs72546319 0.00117
NM_198578.4(LRRK2):c.6510C>A (p.Gly2170=) rs34869625 0.00101
NM_198578.4(LRRK2):c.3777+7C>T rs41286480 0.00097
NM_198578.4(LRRK2):c.4827+9C>A rs113735323 0.00091
NM_198578.4(LRRK2):c.2378G>T (p.Arg793Met) rs35173587 0.00085
NM_198578.4(LRRK2):c.2322G>A (p.Ala774=) rs146103273 0.00066
NM_198578.4(LRRK2):c.7153G>A (p.Gly2385Arg) rs34778348 0.00058
NM_198578.4(LRRK2):c.825T>C (p.His275=) rs72546315 0.00041
NM_198578.4(LRRK2):c.7320A>G (p.Ser2440=) rs144027504 0.00039
NM_198578.4(LRRK2):c.7429C>T (p.Arg2477Trp) rs138780308 0.00035
NM_198578.4(LRRK2):c.364C>T (p.Leu122=) rs41286468 0.00026
NM_198578.4(LRRK2):c.1256C>T (p.Ala419Val) rs34594498 0.00025
NM_198578.4(LRRK2):c.7462+15G>C rs200420425 0.00025
NM_198578.4(LRRK2):c.2264C>T (p.Pro755Leu) rs34410987 0.00023
NM_198578.4(LRRK2):c.2594C>T (p.Ser865Phe) rs142700458 0.00023
NM_198578.4(LRRK2):c.3429C>T (p.Ser1143=) rs142989436 0.00019
NM_198578.4(LRRK2):c.1561A>G (p.Arg521Gly) rs35328937 0.00016
NM_198578.4(LRRK2):c.*470G>T rs200678400 0.00013
NM_198578.4(LRRK2):c.7483G>A (p.Val2495Ile) rs150062967 0.00011
NM_198578.4(LRRK2):c.4959A>G (p.Leu1653=) rs111503579 0.00004
NM_198578.4(LRRK2):c.6929C>T (p.Thr2310Met) rs200002022 0.00004
NM_198578.4(LRRK2):c.5080C>T (p.Leu1694=) rs746878736 0.00003
NM_198578.4(LRRK2):c.5385G>A (p.Leu1795=) rs111910483 0.00002
NM_198578.4(LRRK2):c.3496+9T>G rs560559629 0.00001
NM_198578.4(LRRK2):c.4537-6T>C rs779382508 0.00001
NM_198578.4(LRRK2):c.4611G>A (p.Glu1537=) rs575429866 0.00001
NM_198578.4(LRRK2):c.834A>G (p.Thr278=) rs199626996 0.00001
NM_198578.4(LRRK2):c.*148T>C rs202205832
NM_198578.4(LRRK2):c.1095C>T (p.His365=)
NM_198578.4(LRRK2):c.1102-15del
NM_198578.4(LRRK2):c.1289-13T>A
NM_198578.4(LRRK2):c.1802-11del rs200529791
NM_198578.4(LRRK2):c.1802-11dup rs200529791
NM_198578.4(LRRK2):c.2283A>G (p.Leu761=)
NM_198578.4(LRRK2):c.2501-9dup rs36220740
NM_198578.4(LRRK2):c.2604G>A (p.Val868=)
NM_198578.4(LRRK2):c.2689+19_2689+20del
NM_198578.4(LRRK2):c.2689+19_2689+20dup rs66810434
NM_198578.4(LRRK2):c.2689+20del
NM_198578.4(LRRK2):c.2689+20dup rs66810434
NM_198578.4(LRRK2):c.2879-9del rs766368406
NM_198578.4(LRRK2):c.3497-8del rs201739149
NM_198578.4(LRRK2):c.3497-8dup rs201739149
NM_198578.4(LRRK2):c.3778-10dup
NM_198578.4(LRRK2):c.4193G>A (p.Arg1398His) rs7133914
NM_198578.4(LRRK2):c.4883G>C (p.Arg1628Pro) rs33949390
NM_198578.4(LRRK2):c.6141T>C (p.Asn2047=)
NM_198578.4(LRRK2):c.6281-3dup rs780258764
NM_198578.4(LRRK2):c.6382-20T>C
NM_198578.4(LRRK2):c.6844-8dup rs72546334
NM_198578.4(LRRK2):c.6844-9_6844-8dup rs72546334
NM_198578.4(LRRK2):c.7029-16T>C
NM_198578.4(LRRK2):c.7029-9del rs11317573
NM_198578.4(LRRK2):c.936G>T (p.Ala312=) rs41286466

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