List of variants in gene ATM reported as uncertain significance for Breast and/or ovarian cancer

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 74

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HGVS	dbSNP	gnomAD frequency
NM_000051.4(ATM):c.1073A>G (p.Asn358Ser)	rs149636614	0.00079
NM_000051.4(ATM):c.4424A>G (p.Tyr1475Cys)	rs34640941	0.00053
NM_000051.4(ATM):c.4709T>C (p.Val1570Ala)	rs140856217	0.00046
NM_000051.4(ATM):c.2494C>T (p.Arg832Cys)	rs2229022	0.00032
NM_000051.4(ATM):c.4324T>C (p.Tyr1442His)	rs201666889	0.00029
NM_000051.4(ATM):c.3014A>G (p.Asn1005Ser)	rs146531614	0.00028
NM_000051.4(ATM):c.2522A>C (p.Asp841Ala)	rs587781812	0.00017
NM_000051.4(ATM):c.2887A>G (p.Met963Val)	rs374353016	0.00015
NM_000051.4(ATM):c.3806A>G (p.Lys1269Arg)	rs146017595	0.00014
NM_000051.4(ATM):c.4066A>G (p.Asn1356Asp)	rs147600485	0.00014
NM_000051.4(ATM):c.5089A>G (p.Thr1697Ala)	rs142455912	0.00014
NM_000051.4(ATM):c.2021A>G (p.His674Arg)	rs201762714	0.00007
NM_000051.4(ATM):c.749G>A (p.Arg250Gln)	rs56123940	0.00007
NM_000051.4(ATM):c.1010G>A (p.Arg337His)	rs202160435	0.00006
NM_000051.4(ATM):c.2275A>G (p.Ser759Gly)	rs148705269	0.00006
NM_000051.4(ATM):c.610G>A (p.Gly204Arg)	rs147915571	0.00006
NM_000051.4(ATM):c.1516G>T (p.Gly506Cys)	rs587779816	0.00004
NM_000051.4(ATM):c.202A>G (p.Ile68Val)	rs35389822	0.00004
NM_000051.4(ATM):c.2418G>T (p.Leu806Phe)	rs587781296	0.00004
NM_000051.4(ATM):c.2689T>A (p.Phe897Ile)	rs147122522	0.00004
NM_000051.4(ATM):c.2836A>G (p.Met946Val)	rs587781992	0.00004
NM_000051.4(ATM):c.5278A>G (p.Met1760Val)	rs151327241	0.00004
NM_000051.4(ATM):c.1440A>C (p.Leu480Phe)	rs370240037	0.00003
NM_000051.4(ATM):c.2222A>G (p.Tyr741Cys)	rs878853492	0.00003
NM_000051.4(ATM):c.2396C>T (p.Ala799Val)	rs199954262	0.00003
NM_000051.4(ATM):c.2519A>T (p.Asp840Val)	rs786202605	0.00003
NM_000051.4(ATM):c.2159G>A (p.Arg720His)	rs55830714	0.00002
NM_000051.4(ATM):c.3577G>A (p.Val1193Ile)	rs779148780	0.00002
NM_000051.4(ATM):c.1021G>A (p.Val341Ile)	rs200601781	0.00001
NM_000051.4(ATM):c.1675A>G (p.Ile559Val)	rs1060501545	0.00001
NM_000051.4(ATM):c.1880T>G (p.Phe627Cys)	rs546087885	0.00001
NM_000051.4(ATM):c.1898+3A>G	rs200169643	0.00001
NM_000051.4(ATM):c.1899-10T>G	rs763685190	0.00001
NM_000051.4(ATM):c.1960C>A (p.Gln654Lys)	rs528165789	0.00001
NM_000051.4(ATM):c.2062G>A (p.Glu688Lys)	rs769338089	0.00001
NM_000051.4(ATM):c.2074C>T (p.Arg692Cys)	rs765965513	0.00001
NM_000051.4(ATM):c.2236T>C (p.Phe746Leu)	rs1017383703	0.00001
NM_000051.4(ATM):c.2924A>G (p.Asn975Ser)	rs730881354	0.00001
NM_000051.4(ATM):c.4110-4T>C	rs777186156	0.00001
NM_000051.4(ATM):c.4420C>G (p.His1474Asp)	rs587779840	0.00001
NM_000051.4(ATM):c.4703A>G (p.His1568Arg)	rs368830730	0.00001
NM_000051.4(ATM):c.4910-16A>T	rs866500582	0.00001
NM_000051.4(ATM):c.5056A>G (p.Ile1686Val)	rs145453814	0.00001
NM_000051.4(ATM):c.5063T>C (p.Ile1688Thr)	rs199836342	0.00001
NM_000051.4(ATM):c.5080G>A (p.Ala1694Thr)	rs756197350	0.00001
NM_000051.4(ATM):c.5417T>C (p.Ile1806Thr)	rs773546064	0.00001
NM_000051.4(ATM):c.5524C>T (p.Leu1842Phe)	rs956546711	0.00001
NM_000051.4(ATM):c.1079A>C (p.Asp360Ala)	rs775767808
NM_000051.4(ATM):c.1166T>C (p.Ile389Thr)	rs757486696
NM_000051.4(ATM):c.1354A>G (p.Thr452Ala)	rs1324524747
NM_000051.4(ATM):c.137A>G (p.His46Arg)	rs1591447177
NM_000051.4(ATM):c.1504G>A (p.Ala502Thr)	rs2080112799
NM_000051.4(ATM):c.1642A>G (p.Thr548Ala)	rs878853486
NM_000051.4(ATM):c.1703G>A (p.Arg568Lys)	rs200381392
NM_000051.4(ATM):c.2033T>C (p.Ile678Thr)	rs1485409783
NM_000051.4(ATM):c.2158C>T (p.Arg720Cys)	rs565622131
NM_000051.4(ATM):c.2411T>G (p.Leu804Arg)
NM_000051.4(ATM):c.2926G>A (p.Val976Met)	rs1178628574
NM_000051.4(ATM):c.3153+9T>C	rs770464168
NM_000051.4(ATM):c.3154-4G>A	rs199543313
NM_000051.4(ATM):c.3226C>G (p.Gln1076Glu)	rs2135571727
NM_000051.4(ATM):c.332-7G>T	rs1591474291
NM_000051.4(ATM):c.3343C>T (p.Leu1115Phe)	rs752339681
NM_000051.4(ATM):c.3993+6G>A	rs878853508
NM_000051.4(ATM):c.399T>A (p.Asn133Lys)	rs1555059218
NM_000051.4(ATM):c.4151A>T (p.His1384Leu)
NM_000051.4(ATM):c.4196C>G (p.Thr1399Ser)	rs786203761
NM_000051.4(ATM):c.4627A>G (p.Lys1543Glu)
NM_000051.4(ATM):c.4932G>C (p.Met1644Ile)	rs730881371
NM_000051.4(ATM):c.508G>A (p.Val170Met)	rs786202781
NM_000051.4(ATM):c.5178-7T>C	rs1555105564
NM_000051.4(ATM):c.649_651dup (p.Ile217dup)	rs1565369864
NM_000051.4(ATM):c.68G>A (p.Arg23Gln)	rs587779858
NM_000051.4(ATM):c.974A>G (p.His325Arg)	rs1565375244

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