List of variants in gene PALB2 reported as uncertain significance for Breast and/or ovarian cancer

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 30

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HGVS	dbSNP	gnomAD frequency
NM_024675.4(PALB2):c.298C>T (p.Leu100Phe)	rs61756147	0.00021
NM_024675.4(PALB2):c.11C>T (p.Pro4Leu)	rs45619737	0.00010
NM_024675.4(PALB2):c.1544A>G (p.Lys515Arg)	rs515726072	0.00009
NM_024675.4(PALB2):c.2509G>A (p.Glu837Lys)	rs587778587	0.00008
NM_024675.4(PALB2):c.1001A>G (p.Tyr334Cys)	rs200620434	0.00006
NM_024675.4(PALB2):c.2773G>C (p.Val925Leu)	rs180177125	0.00005
NM_024675.4(PALB2):c.2289G>C (p.Leu763Phe)	rs373478248	0.00004
NM_024675.4(PALB2):c.1189A>T (p.Thr397Ser)	rs367578415	0.00003
NM_024675.4(PALB2):c.1647C>A (p.His549Gln)	rs747842085	0.00003
NM_024675.4(PALB2):c.1756G>A (p.Asp586Asn)	rs587781954	0.00003
NM_024675.4(PALB2):c.3473A>G (p.His1158Arg)	rs45505500	0.00003
NM_024675.4(PALB2):c.1213C>G (p.Pro405Ala)	rs545119348	0.00002
NM_024675.4(PALB2):c.149A>C (p.Lys50Thr)	rs763598472	0.00002
NM_024675.4(PALB2):c.2417C>T (p.Pro806Leu)	rs45464991	0.00002
NM_024675.4(PALB2):c.2755G>A (p.Val919Ile)	rs775193384	0.00002
NM_024675.4(PALB2):c.2087C>T (p.Thr696Met)	rs587780820	0.00001
NM_024675.4(PALB2):c.2207C>T (p.Ala736Val)	rs746056001	0.00001
NM_024675.4(PALB2):c.2514+3A>G	rs515726088	0.00001
NM_024675.4(PALB2):c.2586G>C (p.Lys862Asn)	rs876658279	0.00001
NM_024675.4(PALB2):c.3061G>A (p.Gly1021Arg)	rs143808171	0.00001
NM_024675.4(PALB2):c.3073G>A (p.Ala1025Thr)	rs746872839	0.00001
NM_024675.4(PALB2):c.749T>C (p.Leu250Ser)	rs774675771	0.00001
NM_024675.4(PALB2):c.844A>G (p.Arg282Gly)	rs45447991	0.00001
NM_024675.4(PALB2):c.928A>G (p.Ser310Gly)	rs45561331	0.00001
NM_024675.4(PALB2):c.129G>T (p.Lys43Asn)	rs551111938
NM_024675.4(PALB2):c.1424C>T (p.Ser475Leu)	rs886039479
NM_024675.4(PALB2):c.3202-8G>T	rs367979106
NM_024675.4(PALB2):c.3209T>C (p.Leu1070Pro)	rs863224785
NM_024675.4(PALB2):c.3307G>C (p.Val1103Leu)	rs201657283
NM_024675.4(PALB2):c.3540A>G (p.Ile1180Met)	rs1966395358

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