List of variants in gene BRCA2 reported as pathogenic for Breast carcinoma

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 31

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.5645C>A (p.Ser1882Ter)	rs80358785	0.00002
NM_000059.4(BRCA2):c.9117G>A (p.Pro3039=)	rs28897756	0.00001
NM_000059.4(BRCA2):c.1013del (p.Ala338fs)	rs2137466855
NM_000059.4(BRCA2):c.1189C>T (p.Gln397Ter)	rs760815829
NM_000059.4(BRCA2):c.1364C>G (p.Ser455Ter)	rs2072410817
NM_000059.4(BRCA2):c.1414C>T (p.Gln472Ter)	rs80358429
NM_000059.4(BRCA2):c.1507A>T (p.Lys503Ter)	rs2137472200
NM_000059.4(BRCA2):c.3199del (p.Thr1067fs)	rs80359377
NM_000059.4(BRCA2):c.3751dup (p.Thr1251fs)	rs397507683
NM_000059.4(BRCA2):c.3847_3848del (p.Val1283fs)	rs80359405
NM_000059.4(BRCA2):c.3975_3978dup (p.Ala1327fs)	rs397515636
NM_000059.4(BRCA2):c.4471_4474del (p.Leu1491fs)	rs80359451
NM_000059.4(BRCA2):c.5351dup (p.Asn1784fs)	rs80359507
NM_000059.4(BRCA2):c.5557dup (p.Cys1853fs)	rs587782011
NM_000059.4(BRCA2):c.5621_5624del (p.Ile1874fs)	rs80359526
NM_000059.4(BRCA2):c.6405_6409del (p.Asn2135fs)	rs80359584
NM_000059.4(BRCA2):c.643del (p.Glu215fs)	rs2137458206
NM_000059.4(BRCA2):c.6469C>T (p.Gln2157Ter)	rs397507859
NM_000059.4(BRCA2):c.6478C>T (p.Gln2160Ter)	rs886040658
NM_000059.4(BRCA2):c.6486_6489del (p.Lys2162fs)	rs80359598
NM_000059.4(BRCA2):c.6596_6597delinsA (p.Thr2199fs)	rs1593909229
NM_000059.4(BRCA2):c.7632_7633del (p.Val2545fs)	rs2137566201
NM_000059.4(BRCA2):c.771_775del (p.Asn257fs)	rs80359671
NM_000059.4(BRCA2):c.7877G>A (p.Trp2626Ter)	rs587781506
NM_000059.4(BRCA2):c.8395del (p.Arg2799fs)	rs80359709
NM_000059.4(BRCA2):c.8754+1G>T	rs397508006
NM_000059.4(BRCA2):c.9027del (p.His3010fs)	rs80359742
NM_000059.4(BRCA2):c.9097dup (p.Thr3033fs)	rs397507419
NM_000059.4(BRCA2):c.9118-1G>C	rs886040950
NM_000059.4(BRCA2):c.9317G>A (p.Trp3106Ter)	rs80359205
NM_000059.4(BRCA2):c.9682del (p.Ser3228fs)	rs398122618

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