List of variants in gene CYLD reported as benign for Brooke-Spiegler syndrome

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 42

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HGVS	dbSNP	gnomAD frequency
NM_001378743.1(CYLD):c.2469+26A>G	rs2302759	0.84878
NM_001378743.1(CYLD):c.*4561G>A	rs17314948	0.05808
NM_001378743.1(CYLD):c.2412C>T (p.Asp804=)	rs2066852	0.05803
NM_001378743.1(CYLD):c.*837A>G	rs3743781	0.05586
NM_001378743.1(CYLD):c.2109-10G>A	rs11865799	0.05482
NM_001378743.1(CYLD):c.4888_4889del	rs143814807	0.05112
NM_001378743.1(CYLD):c.*841G>A	rs117537927	0.02264
NM_001378743.1(CYLD):c.*2369G>A	rs16948829	0.01401
NM_001378743.1(CYLD):c.*3739C>G	rs16948836	0.01185
NM_001378743.1(CYLD):c.*2236C>T	rs57638820	0.00896
NM_001378743.1(CYLD):c.1473C>T (p.Ile491=)	rs75757530	0.00802
NM_001378743.1(CYLD):c.*2335T>C	rs9646285	0.00710
NM_001378743.1(CYLD):c.*139G>A	rs148107725	0.00663
NM_001378743.1(CYLD):c.*1831G>A	rs181246559	0.00617
NM_001378743.1(CYLD):c.*3469T>C	rs111951225	0.00586
NM_001378743.1(CYLD):c.*1341T>G	rs140767609	0.00526
NM_001378743.1(CYLD):c.*1575G>A	rs184344245	0.00515
NM_001378743.1(CYLD):c.*3070A>G	rs144667145	0.00435
NM_001378743.1(CYLD):c.*4567C>T	rs113748745	0.00336
NM_001378743.1(CYLD):c.*2710C>T	rs141928186	0.00225
NM_001378743.1(CYLD):c.*1590T>C	rs528844666	0.00218
NM_001378743.1(CYLD):c.*47G>A	rs116979331	0.00200
NM_001378743.1(CYLD):c.*698T>G	rs541975303	0.00173
NM_001378743.1(CYLD):c.*3736G>A	rs567662515	0.00056
NM_001378743.1(CYLD):c.*2615A>G	rs181056407	0.00042
NM_001378743.1(CYLD):c.*5272C>T	rs140875917	0.00030
NM_001378743.1(CYLD):c.126G>A (p.Pro42=)	rs202119806	0.00025
NM_001378743.1(CYLD):c.2469+10C>T	rs374473837	0.00018
NM_001378743.1(CYLD):c.*382T>C	rs142580891	0.00017
NM_001378743.1(CYLD):c.*5086A>G	rs572929759	0.00015
NM_001378743.1(CYLD):c.913+5G>T	rs200435608	0.00012
NM_001378743.1(CYLD):c.*831C>T	rs144877731	0.00009
NM_001378743.1(CYLD):c.*3614C>A	rs372370285	0.00008
NM_001378743.1(CYLD):c.*3679T>C	rs141888517	0.00007
NM_001378743.1(CYLD):c.59T>G (p.Ile20Ser)	rs764097337	0.00005
NM_001378743.1(CYLD):c.1172T>C (p.Ile391Thr)	rs138976689	0.00003
NM_001378743.1(CYLD):c.2319G>A (p.Leu773=)	rs199912760	0.00001
NM_001378743.1(CYLD):c.*2122del	rs74757288
NM_001378743.1(CYLD):c.*2150A>G	rs563954578
NM_001378743.1(CYLD):c.*2646G>A	rs563329143
NM_001378743.1(CYLD):c.1292G>A (p.Gly431Glu)	rs200494719
NM_001378743.1(CYLD):c.922+9C>A	rs528253971

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