Variants studied for Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy type 1

Minimum submission review status:		Collection method:
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Gene type:		Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
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If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
23	2	37	46	28	12	136

Gene and significance breakdown #

Total genes and gene combinations: 2

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
NOTCH3	23	2	37	45	28	12	135
MIR6795, NOTCH3	0	0	0	1	0	0	1

Submitter and significance breakdown #

Total submitters: 11

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Illumina Clinical Services Laboratory,Illumina	2	0	32	46	21	0	101
Mendelics	5	1	3	1	4	0	14
OMIM	12	0	0	0	0	0	12
GenomeConnect - CureCADASIL	0	0	0	0	0	12	12
Athena Diagnostics Inc	0	0	0	0	5	0	5
GeneReviews	3	0	0	0	0	0	3
Bioscientia Institut fuer Medizinische Diagnostik GmbH,Sonic Healthcare	0	0	2	0	0	0	2
Molecular Diagnostics Laboratory, M Health: University of Minnesota	1	1	0	0	0	0	2
ClinVar Staff, National Center for Biotechnology Information (NCBI)	1	0	0	0	0	0	1
Genomic Research Center, Shahid Beheshti University of Medical Sciences	1	0	0	0	0	0	1
UCLA Clinical Genomics Center, UCLA	1	0	0	0	0	0	1

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