Variants studied for Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy type 1

Minimum submission review status:		Collection method:
Minimum conflict level:
Gene type:		Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
26	7	90	42	64	18	231

Gene and significance breakdown #

Total genes and gene combinations: 2

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
NOTCH3	26	7	90	42	63	18	230
MIR6795, NOTCH3	0	0	0	0	1	0	1

Submitter and significance breakdown #

Total submitters: 14

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Illumina Clinical Services Laboratory,Illumina	2	0	83	42	59	0	186
GenomeConnect - CureCADASIL	0	0	0	0	0	18	18
Mendelics	5	1	3	1	4	0	14
OMIM	12	0	0	0	0	0	12
Institute of Human Genetics, University of Leipzig Medical Center	3	5	4	0	0	0	12
Athena Diagnostics Inc	0	0	0	0	5	0	5
GeneReviews	3	0	0	0	0	0	3
Bioscientia Institut fuer Medizinische Diagnostik GmbH,Sonic Healthcare	0	0	2	0	0	0	2
Molecular Diagnostics Laboratory, M Health Fairview: University of Minnesota	1	1	0	0	0	0	2
ClinVar Staff, National Center for Biotechnology Information (NCBI)	1	0	0	0	0	0	1
Genomic Research Center, Shahid Beheshti University of Medical Sciences	1	0	0	0	0	0	1
UCLA Clinical Genomics Center, UCLA	1	0	0	0	0	0	1
Center for Human Genetics and Laboratory Diagnostics, Dr. Klein, Dr. Rost and Colleagues	1	0	0	0	0	0	1
Department of Neurology,National Cerebral and Cardiovascular Center	1	0	0	0	0	0	1

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