ClinVar Miner

List of variants reported as likely pathogenic for Chronic lymphocytic leukemia

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Total variants: 103
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HGVS dbSNP
NM_000546.5(TP53):c.332T>C (p.Leu111Pro) rs1057519997
NM_000546.5(TP53):c.523C>G (p.Arg175Gly) rs138729528
NM_000546.5(TP53):c.523C>T (p.Arg175Cys) rs138729528
NM_000546.5(TP53):c.577C>G (p.His193Asp) rs876658468
NM_000546.5(TP53):c.577C>T (p.His193Tyr) rs876658468
NM_000546.5(TP53):c.578A>G (p.His193Arg) rs786201838
NM_000546.5(TP53):c.578A>T (p.His193Leu) rs786201838
NM_000546.5(TP53):c.584T>A (p.Ile195Asn) rs760043106
NM_000546.5(TP53):c.584T>C (p.Ile195Thr) rs760043106
NM_000546.5(TP53):c.585C>G (p.Ile195Met) rs1057519994
NM_000546.5(TP53):c.641A>G (p.His214Arg) rs1057519992
NM_000546.5(TP53):c.641A>T (p.His214Leu) rs1057519992
NM_000546.5(TP53):c.712T>C (p.Cys238Arg) rs1057519981
NM_000546.5(TP53):c.712T>G (p.Cys238Gly) rs1057519981
NM_000546.5(TP53):c.713G>A (p.Cys238Tyr) rs730882005
NM_000546.5(TP53):c.713G>C (p.Cys238Ser) rs730882005
NM_000546.5(TP53):c.713G>T (p.Cys238Phe) rs730882005
NM_000546.5(TP53):c.724T>A (p.Cys242Ser) rs1057519982
NM_000546.5(TP53):c.724T>G (p.Cys242Gly) rs1057519982
NM_000546.5(TP53):c.725G>A (p.Cys242Tyr) rs121912655
NM_000546.5(TP53):c.725G>T (p.Cys242Phe) rs121912655
NM_000546.5(TP53):c.742C>T (p.Arg248Trp) rs121912651
NM_000546.5(TP53):c.743G>A (p.Arg248Gln) rs11540652
NM_000546.5(TP53):c.743G>C (p.Arg248Pro) rs11540652
NM_000546.5(TP53):c.743G>T (p.Arg248Leu) rs11540652
NM_000546.5(TP53):c.763A>T (p.Ile255Phe) rs1057519995
NM_000546.5(TP53):c.764T>A (p.Ile255Asn) rs876659675
NM_000546.5(TP53):c.764T>C (p.Ile255Thr) rs876659675
NM_000546.5(TP53):c.797G>T (p.Gly266Val) rs193920774
NM_000546.5(TP53):c.817C>A (p.Arg273Ser) rs121913343
NM_000546.5(TP53):c.818G>A (p.Arg273His) rs28934576
NM_000546.5(TP53):c.818G>C (p.Arg273Pro) rs28934576
NM_000546.5(TP53):c.818G>T (p.Arg273Leu) rs28934576
NM_000546.5(TP53):c.824G>A (p.Cys275Tyr) rs863224451
NM_000546.5(TP53):c.824G>C (p.Cys275Ser) rs863224451
NM_000546.5(TP53):c.824G>T (p.Cys275Phe) rs863224451
NM_000546.5(TP53):c.841G>A (p.Asp281Asn) rs764146326
NM_000546.5(TP53):c.842A>G (p.Asp281Gly) rs587781525
NM_000546.5(TP53):c.842A>T (p.Asp281Val) rs587781525
NM_000546.5(TP53):c.843C>G (p.Asp281Glu) rs1057519984
NM_001013415.2(FBXW7):c.1039C>G (p.Arg347Gly) rs867384286
NM_001013415.2(FBXW7):c.1039C>T (p.Arg347Cys) rs867384286
NM_001013415.2(FBXW7):c.1040G>A (p.Arg347His) rs1057519895
NM_001013415.2(FBXW7):c.1040G>C (p.Arg347Pro) rs1057519895
NM_001013415.2(FBXW7):c.1040G>T (p.Arg347Leu) rs1057519895
NM_001013415.2(FBXW7):c.1159C>A (p.Arg387Ser) rs149680468
NM_001013415.2(FBXW7):c.1159C>G (p.Arg387Gly) rs149680468
NM_001013415.2(FBXW7):c.1160G>T (p.Arg387Leu) rs1057519896
NM_001126112.2(TP53):c.332T>G (p.Leu111Arg) rs1057519997
NM_001126112.2(TP53):c.823T>C (p.Cys275Arg) rs1057519983
NM_001126113.2(TP53):c.332T>A (p.Leu111Gln) rs1057519997
NM_001126113.2(TP53):c.577C>A (p.His193Asn) rs876658468
NM_001126115.1(TP53):c.182A>C (p.His61Pro) rs786201838
NM_001126115.1(TP53):c.187A>T (p.Ile63Phe) rs942158624
NM_001126115.1(TP53):c.400G>C (p.Gly134Arg) rs1057519990
NM_001126115.1(TP53):c.401G>A (p.Gly134Glu) rs193920774
NM_001126115.1(TP53):c.445G>C (p.Asp149His) rs764146326
NM_001126116.1(TP53):c.188T>G (p.Ile63Ser) rs760043106
NM_001126116.1(TP53):c.330C>G (p.Cys110Trp) rs375874539
NM_001126116.1(TP53):c.445G>T (p.Asp149Tyr) rs764146326
NM_001126117.1(TP53):c.368T>G (p.Ile123Ser) rs876659675
NM_001126117.1(TP53):c.446A>C (p.Asp149Ala) rs587781525
NM_001276761.1(TP53):c.625C>G (p.Arg209Gly) rs121912651
NM_002468.5(MYD88):c.755T>C (p.Leu252Pro) rs387907272
NM_002524.3(NRAS):c.182A>C (p.Gln61Pro) rs11554290
NM_002524.3(NRAS):c.182A>G (p.Gln61Arg) rs11554290
NM_002524.3(NRAS):c.183A>T (p.Gln61His) rs121913255
NM_002524.4(NRAS):c.181C>A (p.Gln61Lys) rs121913254
NM_002524.4(NRAS):c.182A>T (p.Gln61Leu) rs11554290
NM_002661.4(PLCG2):c.1993C>T (p.Arg665Trp) rs1057519831
NM_002661.4(PLCG2):c.2535A>C (p.Leu845Phe) rs1057519832
NM_002661.4(PLCG2):c.2535A>T (p.Leu845Phe) rs1057519832
NM_002834.4(PTPN11):c.214G>A (p.Ala72Thr) rs121918453
NM_002834.4(PTPN11):c.215C>A (p.Ala72Asp) rs121918454
NM_002834.4(PTPN11):c.215C>T (p.Ala72Val) rs121918454
NM_003400.3(XPO1):c.1711G>A (p.Glu571Lys) rs1057520009
NM_003400.3(XPO1):c.1712A>C (p.Glu571Ala) rs1057520010
NM_003400.3(XPO1):c.1712A>T (p.Glu571Val) rs1057520010
NM_004333.4(BRAF):c.1391G>A (p.Gly464Glu) rs121913348
NM_004333.4(BRAF):c.1780G>A (p.Asp594Asn) rs397516896
NM_004333.4(BRAF):c.1780G>C (p.Asp594His) rs397516896
NM_004333.4(BRAF):c.1781A>G (p.Asp594Gly) rs121913338
NM_004333.4(BRAF):c.1802A>C (p.Lys601Thr) rs397507484
NM_004333.4(BRAF):c.1803A>C (p.Lys601Asn) rs121913365
NM_004333.5(BRAF):c.1801A>G (p.Lys601Glu) rs121913364
NM_005343.2(HRAS):c.38G>T (p.Gly13Val) rs104894226
NM_005343.3(HRAS):c.181C>G (p.Gln61Glu) rs28933406
NM_005343.3(HRAS):c.182A>C (p.Gln61Pro) rs121913233
NM_005343.3(HRAS):c.182A>T (p.Gln61Leu) rs121913233
NM_005343.3(HRAS):c.37G>C (p.Gly13Arg) rs104894228
NM_005343.3(HRAS):c.38G>C (p.Gly13Ala) rs104894226
NM_005343.4(HRAS):c.37G>T (p.Gly13Cys) rs104894228
NM_006842.2(SF3B2):c.1997A>C (p.His666Pro) rs1057519959
NM_006842.2(SF3B2):c.2099A>G (p.Glu700Gly) rs1057519960
NM_012433.3(SF3B1):c.1873C>G (p.Arg625Gly) rs775623976
NM_012433.3(SF3B1):c.1873C>T (p.Arg625Cys) rs775623976
NM_012433.3(SF3B1):c.1874G>A (p.Arg625His) rs1057519961
NM_012433.3(SF3B1):c.1996A>C (p.Lys666Gln) rs754688962
NM_012433.3(SF3B1):c.1996A>G (p.Lys666Glu) rs754688962
NM_012433.3(SF3B1):c.2225G>A (p.Gly742Asp) rs755415626
NM_033360.3(KRAS):c.183A>T (p.Gln61His) rs17851045
NM_033632.3(FBXW7):c.1513C>T (p.Arg505Cys) rs149680468
NM_033632.3(FBXW7):c.1514G>A (p.Arg505His) rs1057519896

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