List of variants reported as likely benign for Colorectal cancer, susceptibility to, 12; Facial dysmorphism-immunodeficiency-livedo-short stature syndrome; Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, genital anomalies, and immunodeficiency by Fulgent Genetics, Fulgent Genetics

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Total variants: 21

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HGVS	dbSNP	gnomAD frequency
NM_006231.4(POLE):c.2550C>T (p.Ile850=)	rs5744834	0.01438
NM_006231.4(POLE):c.5678+4C>T	rs5744973	0.01405
NM_006231.4(POLE):c.6330+18C>T	rs5745024	0.01301
NM_006231.4(POLE):c.6763A>T (p.Ile2255Phe)	rs73155056	0.00487
NM_006231.4(POLE):c.1359+9G>A	rs75135381	0.00461
NM_006231.4(POLE):c.1359+18C>T	rs5744775	0.00455
NM_006231.4(POLE):c.2468+10C>T	rs5744823	0.00342
NM_006231.4(POLE):c.846C>T (p.Pro282=)	rs5744758	0.00291
NM_006231.4(POLE):c.2561+6T>C	rs116231808	0.00179
NM_006231.4(POLE):c.5124C>T (p.Phe1708=)	rs114891564	0.00140
NM_006231.4(POLE):c.6495C>T (p.Arg2165=)	rs114778730	0.00052
NM_006231.4(POLE):c.720+16T>C	rs200320553	0.00006
NM_006231.4(POLE):c.4011C>T (p.Ser1337=)	rs756716850	0.00005
NM_006231.4(POLE):c.3228C>T (p.Cys1076=)	rs767929667	0.00003
NM_006231.4(POLE):c.5478G>T (p.Arg1826=)	rs537648186	0.00003
NM_006231.4(POLE):c.318T>C (p.Ile106=)	rs770759936	0.00002
NM_006231.4(POLE):c.415C>T (p.Leu139=)	rs1302399839	0.00001
NM_006231.4(POLE):c.5559C>T (p.Ile1853=)	rs1032264693	0.00001
NM_006231.4(POLE):c.2865-5_2865-4del	rs369732588
NM_006231.4(POLE):c.4476C>T (p.His1492=)	rs5744943
NM_006231.4(POLE):c.5570A>G (p.Lys1857Arg)	rs5744971

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