List of variants reported as pathogenic for Familial adenomatous polyposis 2 by Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine

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Total variants: 16

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HGVS	dbSNP	gnomAD frequency
NM_001048174.2(MUTYH):c.1103G>A (p.Gly368Asp)	rs36053993	0.00341
NM_001048174.2(MUTYH):c.452A>G (p.Tyr151Cys)	rs34612342	0.00168
NM_001048174.2(MUTYH):c.849+3A>C	rs587780751	0.00013
NM_001048174.2(MUTYH):c.650G>A (p.Arg217His)	rs140342925	0.00009
NM_001048174.2(MUTYH):c.205C>T (p.Arg69Ter)	rs138775799	0.00004
NM_001048174.2(MUTYH):c.1130C>T (p.Pro377Leu)	rs529008617	0.00003
NM_001048174.2(MUTYH):c.1103-2A>G	rs587781628	0.00001
NM_001048174.2(MUTYH):c.1063del (p.Ala357fs)	rs587778536
NM_001048174.2(MUTYH):c.1143_1144dup (p.Glu382fs)	rs587780078
NM_001048174.2(MUTYH):c.1272del (p.Tyr425fs)	rs1553125243
NM_001048174.2(MUTYH):c.1350GGA[1] (p.Glu452del)	rs587778541
NM_001048174.2(MUTYH):c.1354G>T (p.Glu452Ter)	rs121908381
NM_001048174.2(MUTYH):c.225G>A (p.Trp75Ter)	rs748170941
NM_001048174.2(MUTYH):c.228C>A (p.Tyr76Ter)	rs121908380
NM_001048174.2(MUTYH):c.461G>A (p.Arg154His)	rs143353451
NM_001048174.2(MUTYH):c.479_492+1del	rs766553845

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