ClinVar Miner

List of variants in gene PIK3CA reported as uncertain significance for Familial cancer of breast; Megalencephaly-capillary malformation-polymicrogyria syndrome; Lung carcinoma; Congenital macrodactylia; Seborrheic keratosis; Epidermal nevus; Ovarian neoplasm; CLAPO syndrome; CLOVES syndrome; Carcinoma of colon; Neoplasm of stomach; Cowden syndrome 5; Hepatocellular carcinoma

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
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Total variants: 2

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HGVS	dbSNP	gnomAD frequency
NM_006218.4(PIK3CA):c.1130C>G (p.Pro377Arg)	rs113613074	0.00009
NM_006218.4(PIK3CA):c.436G>A (p.Val146Ile)	rs755969956	0.00001

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