List of variants reported as uncertain significance for Familial cancer of breast by Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein

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Total variants: 29

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HGVS	dbSNP	gnomAD frequency
NM_007194.4(CHEK2):c.470T>C (p.Ile157Thr)	rs17879961	0.00434
NM_032043.3(BRIP1):c.2220G>T (p.Gln740His)	rs45589637	0.00041
NM_000051.4(ATM):c.1595G>A (p.Cys532Tyr)	rs35963548	0.00026
NM_000051.4(ATM):c.8560C>T (p.Arg2854Cys)	rs201958469	0.00013
NM_024675.4(PALB2):c.3257G>A (p.Arg1086Gln)	rs146377793	0.00013
NM_024675.4(PALB2):c.560C>A (p.Pro187His)	rs371582757	0.00006
NM_000051.4(ATM):c.5189G>A (p.Arg1730Gln)	rs373789346	0.00003
NM_000465.4(BARD1):c.1028C>T (p.Thr343Ile)	rs201032007	0.00003
NM_000465.4(BARD1):c.1247T>G (p.Leu416Arg)	rs878853996	0.00003
NM_032043.3(BRIP1):c.1246C>T (p.Arg416Trp)	rs587780225	0.00002
NM_000051.4(ATM):c.1080T>G (p.Asp360Glu)	rs199869975	0.00001
NM_000051.4(ATM):c.4010T>A (p.Ile1337Asn)	rs1060501660	0.00001
NM_000465.4(BARD1):c.986C>G (p.Ser329Cys)	rs905626929	0.00001
NM_024675.4(PALB2):c.1696C>T (p.Arg566Cys)	rs746582620	0.00001
NM_024675.4(PALB2):c.2659A>G (p.Ile887Val)	rs533814557	0.00001
NM_024675.4(PALB2):c.2869A>C (p.Lys957Gln)	rs515726103	0.00001
NM_032043.3(BRIP1):c.3693A>G (p.Ile1231Met)	rs1046992728	0.00001
NM_000051.4(ATM):c.1052A>T (p.Asp351Val)	rs1057521618
NM_000051.4(ATM):c.1921GAA[1] (p.Glu642del)	rs876659575
NM_000051.4(ATM):c.6975G>A (p.Ala2325=)	rs556778314
NM_001142556.2(HMMR):c.1962+7A>G
NM_003579.4(RAD54L):c.1769T>C (p.Met590Thr)
NM_003579.4(RAD54L):c.214G>C (p.Ala72Pro)
NM_003579.4(RAD54L):c.863del (p.Gly288fs)	rs1660118680
NM_005432.4(XRCC3):c.1012C>T (p.Arg338Ter)
NM_007194.4(CHEK2):c.231CCAAGAACCTGAGGA[1] (p.77DQEPE[1])	rs587780181
NM_024675.4(PALB2):c.1226A>G (p.Tyr409Cys)	rs878855097
NM_024675.4(PALB2):c.2506G>A (p.Val836Ile)	rs536644825
NM_024675.4(PALB2):c.728C>G (p.Thr243Ser)

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