ClinVar Miner

List of variants in gene CDK4 reported as likely benign for Familial melanoma

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Gene type:
ClinVar version:
Total variants: 175
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HGVS dbSNP gnomAD frequency
NM_000075.4(CDK4):c.625C>T (p.Arg209Cys) rs140644696 0.00029
NM_000075.4(CDK4):c.423G>C (p.Leu141=) rs760242081 0.00003
NM_000075.4(CDK4):c.549C>T (p.Pro183=) rs778696237 0.00003
NM_000075.4(CDK4):c.84T>C (p.Ser28=) rs763203404 0.00003
NM_000075.4(CDK4):c.279T>C (p.Phe93=) rs1478574297 0.00002
NM_000075.4(CDK4):c.354+9G>T rs771456729 0.00002
NM_000075.4(CDK4):c.632+14A>G rs542680423 0.00002
NM_000075.4(CDK4):c.96G>C (p.Val32=) rs563392051 0.00002
NM_000075.4(CDK4):c.219-10C>T rs759302811 0.00001
NM_000075.4(CDK4):c.219-5G>C rs1286893141 0.00001
NM_000075.4(CDK4):c.219-7T>C rs543798269 0.00001
NM_000075.4(CDK4):c.222G>A (p.Leu74=) rs565645344 0.00001
NM_000075.4(CDK4):c.228C>T (p.Asp76=) rs772531745 0.00001
NM_000075.4(CDK4):c.252C>T (p.Asp84=) rs780590939 0.00001
NM_000075.4(CDK4):c.288A>G (p.Val96=) rs754092304 0.00001
NM_000075.4(CDK4):c.309T>C (p.Tyr103=) rs554603181 0.00001
NM_000075.4(CDK4):c.348G>A (p.Thr116=) rs761353033 0.00001
NM_000075.4(CDK4):c.354+19C>T rs587780884 0.00001
NM_000075.4(CDK4):c.355-12C>T rs1004281478 0.00001
NM_000075.4(CDK4):c.365G>A (p.Arg122His) rs34386532 0.00001
NM_000075.4(CDK4):c.402T>C (p.Asn134=) rs537039467 0.00001
NM_000075.4(CDK4):c.481C>T (p.Leu161=) rs796860515 0.00001
NM_000075.4(CDK4):c.486C>G (p.Ala162=) rs1595110441 0.00001
NM_000075.4(CDK4):c.501C>T (p.Tyr167=) rs1316207187 0.00001
NM_000075.4(CDK4):c.504G>A (p.Gln168=) rs770086242 0.00001
NM_000075.4(CDK4):c.519C>T (p.Pro173=) rs747084709 0.00001
NM_000075.4(CDK4):c.522+19C>T rs1955228699 0.00001
NM_000075.4(CDK4):c.523-11A>G rs958372242 0.00001
NM_000075.4(CDK4):c.523-16T>C rs368524338 0.00001
NM_000075.4(CDK4):c.523-4T>A rs587780667 0.00001
NM_000075.4(CDK4):c.534C>T (p.Leu178=) rs11547327 0.00001
NM_000075.4(CDK4):c.543A>C (p.Arg181=) rs745772539 0.00001
NM_000075.4(CDK4):c.597T>C (p.Ser199=) rs1260582581 0.00001
NM_000075.4(CDK4):c.60G>A (p.Val20=) rs1595111186 0.00001
NM_000075.4(CDK4):c.632+16A>G rs1240250642 0.00001
NM_000075.4(CDK4):c.632+20T>C rs1027049979 0.00001
NM_000075.4(CDK4):c.632+8A>G rs1269709231 0.00001
NM_000075.4(CDK4):c.632+9C>T rs1192976748 0.00001
NM_000075.4(CDK4):c.87C>T (p.Gly29=) rs1555201376 0.00001
NM_000075.4(CDK4):c.102C>G (p.Leu34=) rs758515796
NM_000075.4(CDK4):c.105G>A (p.Lys35=) rs2140388473
NM_000075.4(CDK4):c.111G>A (p.Val37=) rs1456215691
NM_000075.4(CDK4):c.117C>A (p.Val39=) rs1595111112
NM_000075.4(CDK4):c.117C>T (p.Val39=) rs1595111112
NM_000075.4(CDK4):c.12T>C (p.Ser4=) rs1595111261
NM_000075.4(CDK4):c.15A>G (p.Arg5=)
NM_000075.4(CDK4):c.219-11A>G
NM_000075.4(CDK4):c.219-14T>C rs2140387656
NM_000075.4(CDK4):c.219-15dup
NM_000075.4(CDK4):c.219-17G>A rs767249235
NM_000075.4(CDK4):c.219-17G>C rs767249235
NM_000075.4(CDK4):c.219-4T>C rs2140387627
NM_000075.4(CDK4):c.219-5del rs2140387632
NM_000075.4(CDK4):c.219-8C>G
NM_000075.4(CDK4):c.219-9T>C rs2140387639
NM_000075.4(CDK4):c.21G>A (p.Glu7=) rs2140388761
NM_000075.4(CDK4):c.222G>T (p.Leu74=) rs565645344
NM_000075.4(CDK4):c.243C>T (p.Ser81=)
NM_000075.4(CDK4):c.246A>C (p.Arg82=) rs2140387517
NM_000075.4(CDK4):c.249T>G (p.Thr83=)
NM_000075.4(CDK4):c.258G>A (p.Glu86=) rs1247612368
NM_000075.4(CDK4):c.261C>A (p.Ile87=) rs779482890
NM_000075.4(CDK4):c.261C>T (p.Ile87=) rs779482890
NM_000075.4(CDK4):c.264G>A (p.Lys88=) rs2140387452
NM_000075.4(CDK4):c.267A>G (p.Val89=) rs886049715
NM_000075.4(CDK4):c.270C>T (p.Thr90=) rs2140387429
NM_000075.4(CDK4):c.271C>T (p.Leu91=) rs949558438
NM_000075.4(CDK4):c.276G>A (p.Val92=) rs918094121
NM_000075.4(CDK4):c.276G>T (p.Val92=)
NM_000075.4(CDK4):c.27G>A (p.Val9=) rs2140388745
NM_000075.4(CDK4):c.285T>C (p.His95=) rs757492324
NM_000075.4(CDK4):c.297C>T (p.Asp99=) rs1595110736
NM_000075.4(CDK4):c.298C>T (p.Leu100=)
NM_000075.4(CDK4):c.300A>G (p.Leu100=) rs2140387344
NM_000075.4(CDK4):c.306A>C (p.Thr102=) rs201202764
NM_000075.4(CDK4):c.312G>A (p.Leu104=) rs2140387313
NM_000075.4(CDK4):c.324C>T (p.Pro108=)
NM_000075.4(CDK4):c.333C>A (p.Gly111=) rs1595110689
NM_000075.4(CDK4):c.333C>T (p.Gly111=) rs1595110689
NM_000075.4(CDK4):c.339A>T (p.Pro113=) rs2140387235
NM_000075.4(CDK4):c.342C>G (p.Ala114=) rs762471901
NM_000075.4(CDK4):c.342C>T (p.Ala114=) rs762471901
NM_000075.4(CDK4):c.351C>A (p.Ile117=)
NM_000075.4(CDK4):c.354+10G>A rs1955232744
NM_000075.4(CDK4):c.354+11T>G
NM_000075.4(CDK4):c.354+12T>G
NM_000075.4(CDK4):c.354+14G>A
NM_000075.4(CDK4):c.354+15T>C rs2140387135
NM_000075.4(CDK4):c.354+16A>G rs2140387134
NM_000075.4(CDK4):c.354+17G>C
NM_000075.4(CDK4):c.354+18G>A
NM_000075.4(CDK4):c.354+8G>C rs2140387160
NM_000075.4(CDK4):c.354+9G>C rs771456729
NM_000075.4(CDK4):c.355-10T>C rs1595110574
NM_000075.4(CDK4):c.355-13C>G rs2140386844
NM_000075.4(CDK4):c.355-16T>C rs1404144583
NM_000075.4(CDK4):c.355-4C>T rs1406247863
NM_000075.4(CDK4):c.355-7A>C
NM_000075.4(CDK4):c.358C>T (p.Leu120=)
NM_000075.4(CDK4):c.369G>A (p.Gln123=) rs1955231243
NM_000075.4(CDK4):c.372T>C (p.Phe124=) rs748374728
NM_000075.4(CDK4):c.373C>T (p.Leu125=)
NM_000075.4(CDK4):c.375A>G (p.Leu125=) rs2640603
NM_000075.4(CDK4):c.381C>T (p.Gly127=) rs781207390
NM_000075.4(CDK4):c.382C>T (p.Leu128=)
NM_000075.4(CDK4):c.390C>T (p.Phe130=)
NM_000075.4(CDK4):c.399C>T (p.Ala133=) rs2140386689
NM_000075.4(CDK4):c.39T>A (p.Gly13=) rs1595111230
NM_000075.4(CDK4):c.408C>A (p.Ile136=) rs758331285
NM_000075.4(CDK4):c.408C>T (p.Ile136=) rs758331285
NM_000075.4(CDK4):c.420T>C (p.Asp140=) rs863224321
NM_000075.4(CDK4):c.423G>A (p.Leu141=) rs760242081
NM_000075.4(CDK4):c.429A>G (p.Pro143=) rs863224322
NM_000075.4(CDK4):c.42C>T (p.Val14=) rs786203182
NM_000075.4(CDK4):c.435C>T (p.Asn145=)
NM_000075.4(CDK4):c.444G>A (p.Val148=) rs1595110484
NM_000075.4(CDK4):c.444G>T (p.Val148=) rs1595110484
NM_000075.4(CDK4):c.453T>C (p.Gly151=) rs2140386487
NM_000075.4(CDK4):c.462C>G (p.Val154=) rs1190412756
NM_000075.4(CDK4):c.465G>A (p.Lys155=) rs2140386451
NM_000075.4(CDK4):c.471T>C (p.Ala157=) rs2140386433
NM_000075.4(CDK4):c.483G>A (p.Leu161=)
NM_000075.4(CDK4):c.48C>G (p.Ala16=) rs1311074831
NM_000075.4(CDK4):c.48C>T (p.Ala16=)
NM_000075.4(CDK4):c.513T>C (p.Leu171=) rs748319770
NM_000075.4(CDK4):c.51T>C (p.Tyr17=) rs2140388654
NM_000075.4(CDK4):c.522+15G>A
NM_000075.4(CDK4):c.522+16G>A
NM_000075.4(CDK4):c.522+17T>C rs2140386235
NM_000075.4(CDK4):c.522+18A>G rs1555201289
NM_000075.4(CDK4):c.522+20C>T rs2140386226
NM_000075.4(CDK4):c.522+7A>G rs1294665075
NM_000075.4(CDK4):c.522+9A>C rs2140386258
NM_000075.4(CDK4):c.523-10T>A
NM_000075.4(CDK4):c.523-10T>C rs1060504384
NM_000075.4(CDK4):c.523-15T>G
NM_000075.4(CDK4):c.523-17C>T
NM_000075.4(CDK4):c.523-20A>G
NM_000075.4(CDK4):c.523-20A>T rs1595110299
NM_000075.4(CDK4):c.523-7C>T rs2140385923
NM_000075.4(CDK4):c.531A>C (p.Thr177=)
NM_000075.4(CDK4):c.531A>G (p.Thr177=) rs2140385880
NM_000075.4(CDK4):c.534C>G (p.Leu178=) rs11547327
NM_000075.4(CDK4):c.549C>G (p.Pro183=) rs778696237
NM_000075.4(CDK4):c.54G>A (p.Gly18=)
NM_000075.4(CDK4):c.552A>G (p.Glu184=) rs2140385820
NM_000075.4(CDK4):c.561G>T (p.Leu187=) rs864622342
NM_000075.4(CDK4):c.564G>A (p.Gln188=) rs1057521685
NM_000075.4(CDK4):c.567C>T (p.Ser189=) rs144422354
NM_000075.4(CDK4):c.570A>C (p.Thr190=) rs1428628208
NM_000075.4(CDK4):c.573T>C (p.Tyr191=) rs878853623
NM_000075.4(CDK4):c.576A>G (p.Ala192=)
NM_000075.4(CDK4):c.57A>G (p.Thr19=)
NM_000075.4(CDK4):c.588C>T (p.Asp196=) rs2140385708
NM_000075.4(CDK4):c.600T>G (p.Val200=) rs2140385676
NM_000075.4(CDK4):c.603C>G (p.Gly201=) rs2140385667
NM_000075.4(CDK4):c.609C>A (p.Ile203=) rs864622504
NM_000075.4(CDK4):c.612T>C (p.Phe204=) rs1555201266
NM_000075.4(CDK4):c.630A>C (p.Arg210=) rs1012477745
NM_000075.4(CDK4):c.630A>G (p.Arg210=) rs1012477745
NM_000075.4(CDK4):c.632+10C>G rs1367377055
NM_000075.4(CDK4):c.632+11C>A
NM_000075.4(CDK4):c.632+13C>T
NM_000075.4(CDK4):c.632+15T>A
NM_000075.4(CDK4):c.632+15_632+16del rs1955225343
NM_000075.4(CDK4):c.632+19C>G rs1027122710
NM_000075.4(CDK4):c.632+19C>T
NM_000075.4(CDK4):c.632+20T>A
NM_000075.4(CDK4):c.632+5dup rs1555201260
NM_000075.4(CDK4):c.632+7G>A rs1955225535
NM_000075.4(CDK4):c.6T>A (p.Ala2=) rs1057523632
NM_000075.4(CDK4):c.78C>T (p.Pro26=) rs1057523487
NM_000075.4(CDK4):c.81C>T (p.His27=)
NM_000075.4(CDK4):c.90C>T (p.His30=) rs2140388517
NM_000075.4(CDK4):c.93T>C (p.Phe31=)

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